obese_Mc4r<tm2Lowl>/Mc4r<tm2Lowl>,Tg(Sim1-cre)1Lowl/0

http://metadb.riken.jp/0001261I129S4SvJaeSor129S6SvEvTacC57BL6FVBNMc4rtm2LowlMc4rtm2LowlTgSim1cre1Lowl0Mc4rtm2LowlTgSim1cre1Lowl

obese_Mc4r<tm2Lowl>/Mc4r<tm2Lowl>,Tg(Sim1-cre)1Lowl/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• melanocortin 4 receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:99457
• transgene insertion 1, Bradford B Lowell
  http://metadb.riken.jp/db/mgi_rdf/MGI:3692524

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Mc4r<tm2Lowl>/Mc4r<tm2Lowl>,Tg(Sim1-cre)1Lowl/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Mc4r<tm2Lowl>|Tg(Sim1-cre)1Lowl

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• obese
  http://purl.obolibrary.org/obo/MP_0001261

文献

http://purl.org/net/cito/citesAsAuthority

• Bhavik P. Shah, et.al., MC4R-expressing glutamatergic neurons in the paraventricular hypothalamus regulate feeding and are synaptically connected to the parabrachial nucleus., Proceedings of the National Academy of Sciences of the United States of America, 2014, 111
  http://rdf.ncbi.nlm.nih.gov/pubmed/25157144