obese_Mc4r<tm1Lowl>/Mc4r<tm1Lowl>,Pdyn<tm1.1(cre)Mjkr>/Pdyn<+>

http://metadb.riken.jp/0001261I129S4SvJaeSor129S6SvEvTacC57BL6Mc4rtm1LowlMc4rtm1LowlPdyntm11creMjkrPdynPdynMc4rtm1LowlPdyntm11creMjkr

obese_Mc4r<tm1Lowl>/Mc4r<tm1Lowl>,Pdyn<tm1.1(cre)Mjkr>/Pdyn<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• prodynorphin
  http://metadb.riken.jp/db/mgi_rdf/MGI:97535
• melanocortin 4 receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:99457

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Mc4r<tm1Lowl>/Mc4r<tm1Lowl>,Pdyn<tm1.1(cre)Mjkr>/Pdyn<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pdyn<+>|Mc4r<tm1Lowl>|Pdyn<tm1.1(cre)Mjkr>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• obese
  http://purl.obolibrary.org/obo/MP_0001261

文献

http://purl.org/net/cito/citesAsAuthority

• Bhavik P. Shah, et.al., MC4R-expressing glutamatergic neurons in the paraventricular hypothalamus regulate feeding and are synaptically connected to the parabrachial nucleus., Proceedings of the National Academy of Sciences of the United States of America, 2014, 111
  http://rdf.ncbi.nlm.nih.gov/pubmed/25157144