decreased body weight_Ghr<tm1Jjk>/Ghr<tm1Jjk>

http://metadb.riken.jp/0001262I129P2OlaHsdBALBcGhrtm1JjkGhrtm1JjkGhrtm1Jjk

decreased body weight_Ghr<tm1Jjk>/Ghr<tm1Jjk>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• growth hormone receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:95708

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ghr<tm1Jjk>/Ghr<tm1Jjk>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ghr<tm1Jjk>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * BALB/c

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased body weight
  http://purl.obolibrary.org/obo/MP_0001262

文献

http://purl.org/net/cito/citesAsAuthority

• V. Chandrashekar, et.al., Pituitary and testicular function in growth hormone receptor gene knockout mice., Endocrinology, 1999, 140
  http://rdf.ncbi.nlm.nih.gov/pubmed/10067829
• Emil. Egecioglu, et.al., Growth hormone receptor deficiency results in blunted ghrelin feeding response, obesity, and hypolipidemia in mice., American journal of physiology. Endocrinology and metabolism, 2006, 290
  http://rdf.ncbi.nlm.nih.gov/pubmed/16174655
• K T. Coschigano, et.al., Assessment of growth parameters and life span of GHR/BP gene-disrupted mice., Endocrinology, 2000, 141
  http://rdf.ncbi.nlm.nih.gov/pubmed/10875265
• F P. Dominici, et.al., Compensatory alterations of insulin signal transduction in liver of growth hormone receptor knockout mice., The Journal of endocrinology, 2000, 166
  http://rdf.ncbi.nlm.nih.gov/pubmed/10974652
• Darlene E. Berryman, et.al., Comparing adiposity profiles in three mouse models with altered GH signaling., Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society, 2004, 14
  http://rdf.ncbi.nlm.nih.gov/pubmed/15231300
• http://rdf.ncbi.nlm.nih.gov/pubmed/12185100
• Ashley S. Izzard, et.al., The cardiovascular phenotype of a mouse model of acromegaly., Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society, 2009, 19
  http://rdf.ncbi.nlm.nih.gov/pubmed/19269870