decreased body weight_Dlst<Gt1Lex>/Dlst<+>,Tg(PRNP-APPSweInd)19959Dwst/0

http://metadb.riken.jp/0001262I129S6SvEvTacFVBNDlstGt1LexDlstTgPRNPAPPSweInd19959Dwst0TgPRNPAPPSweInd19959DwstDlstDlstGt1Lex

decreased body weight_Dlst<Gt1Lex>/Dlst<+>,Tg(PRNP-APPSweInd)19959Dwst/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 19959, David Westaway
  http://metadb.riken.jp/db/mgi_rdf/MGI:4367785
• dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
  http://metadb.riken.jp/db/mgi_rdf/MGI:1926170

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Dlst<Gt1Lex>/Dlst<+>,Tg(PRNP-APPSweInd)19959Dwst/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(PRNP-APPSweInd)19959Dwst|Dlst<+>|Dlst<Gt1Lex>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased body weight
  http://purl.obolibrary.org/obo/MP_0001262

文献

http://purl.org/net/cito/citesAsAuthority

• Magali. Dumont, et.al., Mitochondrial dihydrolipoyl succinyltransferase deficiency accelerates amyloid pathology and memory deficit in a transgenic mouse model of amyloid deposition., Free radical biology & medicine, 2009, 47
  http://rdf.ncbi.nlm.nih.gov/pubmed/19596066