distended abdomen_Cdkn2a<tm1.1Gsu>/Cdkn2a<tm1.1Gsu>,Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)6Tuv/0

http://metadb.riken.jp/0001270I129S4SvJae129S4SvJaeSorC57BL6JFVBNCdkn2atm11GsuCdkn2atm11GsuKrastm4TyjKrasTgPdx1cre6Tuv0KrasKrastm4TyjTgPdx1cre6TuvCdkn2atm11Gsu

distended abdomen_Cdkn2a<tm1.1Gsu>/Cdkn2a<tm1.1Gsu>,Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)6Tuv/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• Kirsten rat sarcoma viral oncogene homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:96680
• cyclin-dependent kinase inhibitor 2A
  http://metadb.riken.jp/db/mgi_rdf/MGI:104738
• transgene insertion 6, David A Tuveson
  http://metadb.riken.jp/db/mgi_rdf/MGI:5437123

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdkn2a<tm1.1Gsu>/Cdkn2a<tm1.1Gsu>,Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)6Tuv/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Kras<+>|Kras<tm4Tyj>|Tg(Pdx1-cre)6Tuv|Cdkn2a<tm1.1Gsu>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * 129S4/SvJaeSor * C57BL/6J * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• distended abdomen
  http://purl.obolibrary.org/obo/MP_0001270

文献

http://purl.org/net/cito/citesAsAuthority

• Wanglong. Qiu, et.al., Disruption of p16 and activation of Kras in pancreas increase ductal adenocarcinoma formation and metastasis in vivo., Oncotarget, 2011, 2
  http://rdf.ncbi.nlm.nih.gov/pubmed/22113502