increased metastatic potential_Pten<tm2Mak>/Pten<tm2Mak>,Tg(KLK3-cre)13Saa/0

http://metadb.riken.jp/0001272I129P2OlaHsdC57BL6Ptentm2MakPtentm2MakTgKLK3cre13Saa0Ptentm2MakTgKLK3cre13Saa

increased metastatic potential_Pten<tm2Mak>/Pten<tm2Mak>,Tg(KLK3-cre)13Saa/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 13, Sarki A Abdulkadir
  http://metadb.riken.jp/db/mgi_rdf/MGI:2450262
• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pten<tm2Mak>/Pten<tm2Mak>,Tg(KLK3-cre)13Saa/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pten<tm2Mak>|Tg(KLK3-cre)13Saa

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased metastatic potential
  http://purl.obolibrary.org/obo/MP_0001272

文献

http://purl.org/net/cito/citesAsAuthority

• Marco A. De Velasco, et.al., Androgen deprivation induces phenotypic plasticity and promotes resistance to molecular targeted therapy in a PTEN-deficient mouse model of prostate cancer., Carcinogenesis, 2014, 35
  http://rdf.ncbi.nlm.nih.gov/pubmed/24986896