increased metastatic potential_Dcc<tm1Nki>/Dcc<tm1Nki>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(KRT14-cre)8Brn/?

http://metadb.riken.jp/0001272I129P2OlaHsdFVBNDcctm1NkiDcctm1NkiTrp53tm1BrnTrp53tm1BrnTgKRT14cre8BrnTgKRT14cre8BrnDcctm1NkiTrp53tm1Brn

increased metastatic potential_Dcc<tm1Nki>/Dcc<tm1Nki>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(KRT14-cre)8Brn/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• deleted in colorectal carcinoma
  http://metadb.riken.jp/db/mgi_rdf/MGI:94869
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• transgene insertion 8, Anton Berns
  http://metadb.riken.jp/db/mgi_rdf/MGI:2177242

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Dcc<tm1Nki>/Dcc<tm1Nki>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(KRT14-cre)8Brn/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(KRT14-cre)8Brn|Dcc<tm1Nki>|Trp53<tm1Brn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased metastatic potential
  http://purl.obolibrary.org/obo/MP_0001272

文献

http://purl.org/net/cito/citesAsAuthority

• Paul. Krimpenfort, et.al., Deleted in colorectal carcinoma suppresses metastasis in p53-deficient mammary tumours., Nature, 2012, 482
  http://rdf.ncbi.nlm.nih.gov/pubmed/22358843