increased metastatic potential_Erbb2<tm8(Erbb2)Mul>/Erbb2<+>,Pten<tm1Hwu>/Pten<+>,Tg(MMTV-cre)7Mul/0

http://metadb.riken.jp/0001272I129S1Sv129S4SvJae129X1SvJFVBNErbb2tm8Erbb2MulErbb2Ptentm1HwuPtenTgMMTVcre7Mul0PtenPtentm1HwuErbb2Erbb2tm8Erbb2MulTgMMTVcre7Mul

increased metastatic potential_Erbb2<tm8(Erbb2)Mul>/Erbb2<+>,Pten<tm1Hwu>/Pten<+>,Tg(MMTV-cre)7Mul/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583
• transgene insertion 7, William J Muller
  http://metadb.riken.jp/db/mgi_rdf/MGI:3589277
• erb-b2 receptor tyrosine kinase 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:95410

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Erbb2<tm8(Erbb2)Mul>/Erbb2<+>,Pten<tm1Hwu>/Pten<+>,Tg(MMTV-cre)7Mul/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pten<+>|Pten<tm1Hwu>|Erbb2<+>|Erbb2<tm8(Erbb2)Mul>|Tg(MMTV-cre)7Mul

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased metastatic potential
  http://purl.obolibrary.org/obo/MP_0001272

文献

http://purl.org/net/cito/citesAsAuthority

• Nathalie. Dourdin, et.al., Phosphatase and tensin homologue deleted on chromosome 10 deficiency accelerates tumor induction in a mouse model of ErbB-2 mammary tumorigenesis., Cancer research, 2008, 68
  http://rdf.ncbi.nlm.nih.gov/pubmed/18381417