increased metastatic potential_Mtbp<tm1Glo>/Mtbp<+>,Trp53<tm1Tyj>/Trp53<+>

http://metadb.riken.jp/0001272I129S2SvPas129S7SvEvBrdC57BL6JMtbptm1GloMtbpTrp53tm1TyjTrp53Trp53tm1TyjTrp53Mtbptm1GloMtbp

increased metastatic potential_Mtbp<tm1Glo>/Mtbp<+>,Trp53<tm1Tyj>/Trp53<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• Mdm2, transformed 3T3 cell double minute p53 binding protein
  http://metadb.riken.jp/db/mgi_rdf/MGI:2146005

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Mtbp<tm1Glo>/Mtbp<+>,Trp53<tm1Tyj>/Trp53<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<tm1Tyj>|Trp53<+>|Mtbp<tm1Glo>|Mtbp<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased metastatic potential
  http://purl.obolibrary.org/obo/MP_0001272

文献

http://purl.org/net/cito/citesAsAuthority

• T. Iwakuma, et.al., Mtbp haploinsufficiency in mice increases tumor metastasis., Oncogene, 2008, 27
  http://rdf.ncbi.nlm.nih.gov/pubmed/17906694