increased metastatic potential_Aes<tm1.1Mmt>/Aes<tm1.1Mmt>,Apc<tm1Mmt>/Apc<+>,Tg(Vil-cre/ERT2)23Syr/0

http://metadb.riken.jp/0001272I129S2SvPasC57BL6DBASJLAestm11MmtAestm11MmtApctm1MmtApcTgVilcreERT223Syr0ApcAestm11MmtApctm1MmtTgVilcreERT223Syr

increased metastatic potential_Aes<tm1.1Mmt>/Aes<tm1.1Mmt>,Apc<tm1Mmt>/Apc<+>,Tg(Vil-cre/ERT2)23Syr/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 23, Sylvie Robine
  http://metadb.riken.jp/db/mgi_rdf/MGI:3053810
• amino-terminal enhancer of split
  http://metadb.riken.jp/db/mgi_rdf/MGI:95806
• adenomatosis polyposis coli
  http://metadb.riken.jp/db/mgi_rdf/MGI:88039

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Aes<tm1.1Mmt>/Aes<tm1.1Mmt>,Apc<tm1Mmt>/Apc<+>,Tg(Vil-cre/ERT2)23Syr/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Apc<+>|Aes<tm1.1Mmt>|Apc<tm1Mmt>|Tg(Vil-cre/ERT2)23Syr

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6 * DBA * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased metastatic potential
  http://purl.obolibrary.org/obo/MP_0001272

文献

http://purl.org/net/cito/citesAsAuthority

• Masahiro. Sonoshita, et.al., Suppression of colon cancer metastasis by Aes through inhibition of Notch signaling., Cancer cell, 2011, 19
  http://rdf.ncbi.nlm.nih.gov/pubmed/21251616