increased metastatic potential_Kras<tm4Tyj>/Kras<+>,Pten<tm1Hwu>/Pten<tm1Hwu>

http://metadb.riken.jp/0001272I129S4SvJaeC57BL6JKrastm4TyjKrasPtentm1HwuPtentm1HwuKrasKrastm4TyjPtentm1Hwu

increased metastatic potential_Kras<tm4Tyj>/Kras<+>,Pten<tm1Hwu>/Pten<tm1Hwu>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• Kirsten rat sarcoma viral oncogene homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:96680
• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Kras<tm4Tyj>/Kras<+>,Pten<tm1Hwu>/Pten<tm1Hwu>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Kras<+>|Kras<tm4Tyj>|Pten<tm1Hwu>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased metastatic potential
  http://purl.obolibrary.org/obo/MP_0001272

文献

http://purl.org/net/cito/citesAsAuthority

• Daniela M. Dinulescu, et.al., Role of K-ras and Pten in the development of mouse models of endometriosis and endometrioid ovarian cancer., Nature medicine, 2005, 11
  http://rdf.ncbi.nlm.nih.gov/pubmed/15619626