decreased metastatic potential_Cpt1c<Gt(XL823)Byg>/Cpt1c<+>,Nf1<tm1Tyj>/Nf1<+>,Trp53<tm1Tyj>/Trp53<+>

http://metadb.riken.jp/0001273I129P2OlaHsd129S2SvPasC57BL6Cpt1cGtXL823BygCpt1cNf1tm1TyjNf1Trp53tm1TyjTrp53Trp53Trp53tm1TyjCpt1cGtXL823BygNf1Nf1tm1TyjCpt1c

decreased metastatic potential_Cpt1c<Gt(XL823)Byg>/Cpt1c<+>,Nf1<tm1Tyj>/Nf1<+>,Trp53<tm1Tyj>/Trp53<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• neurofibromin 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97306
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• carnitine palmitoyltransferase 1c
  http://metadb.riken.jp/db/mgi_rdf/MGI:2446526

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cpt1c<Gt(XL823)Byg>/Cpt1c<+>,Nf1<tm1Tyj>/Nf1<+>,Trp53<tm1Tyj>/Trp53<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<+>|Trp53<tm1Tyj>|Cpt1c<Gt(XL823)Byg>|Nf1<+>|Nf1<tm1Tyj>|Cpt1c<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased metastatic potential
  http://purl.obolibrary.org/obo/MP_0001273

文献

http://purl.org/net/cito/citesAsAuthority

• N. Sanchez-Macedo, et.al., Depletion of the novel p53-target gene carnitine palmitoyltransferase 1C delays tumor growth in the neurofibromatosis type I tumor model., Cell death and differentiation, 2013, 20
  http://rdf.ncbi.nlm.nih.gov/pubmed/23412344