decreased metastatic potential_Shc1<tm6Paw>/Shc1<tm6Paw>,Tg(MMTV-PyVT)634Mul/0

http://metadb.riken.jp/0001273I129S1Sv129X1SvJFVBNShc1tm6PawShc1tm6PawTgMMTVPyVT634Mul0Shc1tm6PawTgMMTVPyVT634Mul

decreased metastatic potential_Shc1<tm6Paw>/Shc1<tm6Paw>,Tg(MMTV-PyVT)634Mul/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• src homology 2 domain-containing transforming protein C1
  http://metadb.riken.jp/db/mgi_rdf/MGI:98296
• transgene insertion 634, William Muller
  http://metadb.riken.jp/db/mgi_rdf/MGI:2679594

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Shc1<tm6Paw>/Shc1<tm6Paw>,Tg(MMTV-PyVT)634Mul/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Shc1<tm6Paw>|Tg(MMTV-PyVT)634Mul

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased metastatic potential
  http://purl.obolibrary.org/obo/MP_0001273

文献

http://purl.org/net/cito/citesAsAuthority

• Josie. Ursini-Siegel, et.al., ShcA signalling is essential for tumour progression in mouse models of human breast cancer., The EMBO journal, 2008, 27
  http://rdf.ncbi.nlm.nih.gov/pubmed/18273058