decreased metastatic potential_Kras<tm4Tyj>/Kras<tm4Tyj>,Mir182<tm1.1Dgk>/Mir182<+>,Trp53<tm1Brn>/Trp53<tm1Brn>

http://metadb.riken.jp/0001273I129Sv129P2OlaHsd129S4SvJaeC57BL6Krastm4TyjKrastm4TyjMir182tm11DgkMir182Trp53tm1BrnTrp53tm1BrnMir182Krastm4TyjMir182tm11DgkTrp53tm1Brn

decreased metastatic potential_Kras<tm4Tyj>/Kras<tm4Tyj>,Mir182<tm1.1Dgk>/Mir182<+>,Trp53<tm1Brn>/Trp53<tm1Brn>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• Kirsten rat sarcoma viral oncogene homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:96680
• microRNA 182
  http://metadb.riken.jp/db/mgi_rdf/MGI:2676846

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Kras<tm4Tyj>/Kras<tm4Tyj>,Mir182<tm1.1Dgk>/Mir182<+>,Trp53<tm1Brn>/Trp53<tm1Brn>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Mir182<+>|Kras<tm4Tyj>|Mir182<tm1.1Dgk>|Trp53<tm1Brn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * 129P2/OlaHsd * 129S4/SvJae * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased metastatic potential
  http://purl.obolibrary.org/obo/MP_0001273

文献

http://purl.org/net/cito/citesAsAuthority

• Mohit. Sachdeva, et.al., MicroRNA-182 drives metastasis of primary sarcomas by targeting multiple genes., The Journal of clinical investigation, 2014, 124
  http://rdf.ncbi.nlm.nih.gov/pubmed/25180607