macrophthalmia_Lama1<tm1Olf>/Lama1<tm1Olf>,Tg(Sox2-cre)1Amc/0

http://metadb.riken.jp/0001296I129S2SvPasC57BL6JCBACD1SwissWebsterLama1tm1OlfLama1tm1OlfTgSox2cre1Amc0Lama1tm1OlfTgSox2cre1Amc

macrophthalmia_Lama1<tm1Olf>/Lama1<tm1Olf>,Tg(Sox2-cre)1Amc/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• laminin, alpha 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:99892
• transgene insertion 1, Andrew P McMahon
  http://metadb.riken.jp/db/mgi_rdf/MGI:2656537

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Lama1<tm1Olf>/Lama1<tm1Olf>,Tg(Sox2-cre)1Amc/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lama1<tm1Olf>|Tg(Sox2-cre)1Amc

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6J * CBA * CD-1 * Swiss Webster

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• macrophthalmia
  http://purl.obolibrary.org/obo/MP_0001296

文献

http://purl.org/net/cito/citesAsAuthority

• Malia M. Edwards, et.al., Mutations in Lama1 disrupt retinal vascular development and inner limiting membrane formation., The Journal of biological chemistry, 2010, 285
  http://rdf.ncbi.nlm.nih.gov/pubmed/20048158