macrophthalmia_Trp53<tm1Brd>/Trp53<tm1Brd>,Tg(Cryaa-NCOA6*)AD5Cve/0

http://metadb.riken.jp/0001296I129S7SvEvBrdFVBNTrp53tm1BrdTrp53tm1BrdTgCryaaNCOA6AD5Cve0Trp53tm1BrdTgCryaaNCOA6AD5Cve

macrophthalmia_Trp53<tm1Brd>/Trp53<tm1Brd>,Tg(Cryaa-NCOA6*)AD5Cve/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion AD5, Ales Cvekl
  http://metadb.riken.jp/db/mgi_rdf/MGI:4837879
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Trp53<tm1Brd>/Trp53<tm1Brd>,Tg(Cryaa-NCOA6*)AD5Cve/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<tm1Brd>|Tg(Cryaa-NCOA6*)AD5Cve

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• macrophthalmia
  http://purl.obolibrary.org/obo/MP_0001296

文献

http://purl.org/net/cito/citesAsAuthority

• Wei-Lin. Wang, et.al., Lens fiber cell differentiation and denucleation are disrupted through expression of the N-terminal nuclear receptor box of NCOA6 and result in p53-dependent and p53-independent apoptosis., Molecular biology of the cell, 2010, 21
  http://rdf.ncbi.nlm.nih.gov/pubmed/20484573