microphthalmia_Egfr<wa2>/Egfr<wa2>,Sos1<tm1Dlb>/Sos1<+>

http://metadb.riken.jp/0001297I129S1Sv129X1SvJB6EiC3SnaAEgfrwa2Wnt3avtEgfrwa2Egfrwa2Sos1tm1DlbSos1Egfrwa2Sos1Sos1tm1Dlb

microphthalmia_Egfr<wa2>/Egfr<wa2>,Sos1<tm1Dlb>/Sos1<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• son of sevenless homolog 1 (Drosophila)
  http://metadb.riken.jp/db/mgi_rdf/MGI:98354
• epidermal growth factor receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:95294

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Egfr<wa2>/Egfr<wa2>,Sos1<tm1Dlb>/Sos1<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Egfr<wa2>|Sos1<+>|Sos1<tm1Dlb>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * B6EiC3Sn-a/A-Egfr<wa2> Wnt3a<vt>

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• microphthalmia
  http://purl.obolibrary.org/obo/MP_0001297

文献

http://purl.org/net/cito/citesAsAuthority

• D Z. Wang, et.al., Mutation in Sos1 dominantly enhances a weak allele of the EGFR, demonstrating a requirement for Sos1 in EGFR signaling and development., Genes & development, 1997, 11
  http://rdf.ncbi.nlm.nih.gov/pubmed/9030684