abnormal lens morphology_Cryaa<tm1.1Ady>/Cryaa<tm1.1Ady>

http://metadb.riken.jp/0001303I129C57BL6Cryaatm11AdyCryaatm11AdyCryaatm11Ady

abnormal lens morphology_Cryaa<tm1.1Ady>/Cryaa<tm1.1Ady>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• crystallin, alpha A
  http://metadb.riken.jp/db/mgi_rdf/MGI:88515

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cryaa<tm1.1Ady>/Cryaa<tm1.1Ady>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cryaa<tm1.1Ady>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal lens morphology
  http://purl.obolibrary.org/obo/MP_0001303

文献

http://purl.org/net/cito/citesAsAuthority

• Jing-hua. Xi, et.al., Mechanism of small heat shock protein function in vivo: a knock-in mouse model demonstrates that the R49C mutation in alpha A-crystallin enhances protein insolubility and cell death., The Journal of biological chemistry, 2008, 283
  http://rdf.ncbi.nlm.nih.gov/pubmed/18056999