abnormal lens morphology_Atf4<tm1Jml>/Atf4<tm1Jml>,Trp53<tm1Brd>/Trp53<tm1Brd>

http://metadb.riken.jp/0001303I129S7SvEvBrd129X1SvJAtf4tm1JmlAtf4tm1JmlTrp53tm1BrdTrp53tm1BrdAtf4tm1JmlTrp53tm1Brd

abnormal lens morphology_Atf4<tm1Jml>/Atf4<tm1Jml>,Trp53<tm1Brd>/Trp53<tm1Brd>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• activating transcription factor 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:88096

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Atf4<tm1Jml>/Atf4<tm1Jml>,Trp53<tm1Brd>/Trp53<tm1Brd>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Atf4<tm1Jml>|Trp53<tm1Brd>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * 129X1/SvJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal lens morphology
  http://purl.obolibrary.org/obo/MP_0001303

文献

http://purl.org/net/cito/citesAsAuthority

• T. Hettmann, et.al., Microphthalmia due to p53-mediated apoptosis of anterior lens epithelial cells in mice lacking the CREB-2 transcription factor., Developmental biology, 2000, 222
  http://rdf.ncbi.nlm.nih.gov/pubmed/10885750