cataract_Sord<C57BL/Lia>/Sord<C57BL/Lia>,Tg(Cryaa-AKR1B1)648Smch/0

http://metadb.riken.jp/0001304IC57BLCBASordC57BLLiaSordC57BLLiaTgCryaaAKR1B1648Smch0TgCryaaAKR1B1648SmchSordC57BLLia

cataract_Sord<C57BL/Lia>/Sord<C57BL/Lia>,Tg(Cryaa-AKR1B1)648Smch/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• sorbitol dehydrogenase
  http://metadb.riken.jp/db/mgi_rdf/MGI:98266
• transgene insertion 648, Stephen SM Chung
  http://metadb.riken.jp/db/mgi_rdf/MGI:3783827

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Sord<C57BL/Lia>/Sord<C57BL/Lia>,Tg(Cryaa-AKR1B1)648Smch/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Cryaa-AKR1B1)648Smch|Sord<C57BL/Lia>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• cataracts
  http://purl.obolibrary.org/obo/MP_0001304

文献

http://purl.org/net/cito/citesAsAuthority

• A Y. Lee, et.al., Demonstration that polyol accumulation is responsible for diabetic cataract by the use of transgenic mice expressing the aldose reductase gene in the lens., Proceedings of the National Academy of Sciences of the United States of America, 1995, 92
  http://rdf.ncbi.nlm.nih.gov/pubmed/7708723