abnormal retina morphology_Atoh7<tm2Gan>/Atoh7<tm2Gan>,Rest<tm1.1Whk>/Rest<tm1.1Whk>,Tg(Six3-cre)69Frty/0

http://metadb.riken.jp/0001325I129S4SvJaeSor129S6SvEvTacC57BL6DBA2Atoh7tm2GanAtoh7tm2GanResttm11WhkResttm11WhkTgSix3cre69Frty0Resttm11WhkAtoh7tm2GanTgSix3cre69Frty

abnormal retina morphology_Atoh7<tm2Gan>/Atoh7<tm2Gan>,Rest<tm1.1Whk>/Rest<tm1.1Whk>,Tg(Six3-cre)69Frty/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 69, Yasuhide Furuta
  http://metadb.riken.jp/db/mgi_rdf/MGI:3574770
• RE1-silencing transcription factor
  http://metadb.riken.jp/db/mgi_rdf/MGI:104897
• atonal bHLH transcription factor 7
  http://metadb.riken.jp/db/mgi_rdf/MGI:1355553

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Atoh7<tm2Gan>/Atoh7<tm2Gan>,Rest<tm1.1Whk>/Rest<tm1.1Whk>,Tg(Six3-cre)69Frty/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Rest<tm1.1Whk>|Atoh7<tm2Gan>|Tg(Six3-cre)69Frty

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal retina morphology
  http://purl.obolibrary.org/obo/MP_0001325

文献

http://purl.org/net/cito/citesAsAuthority

• Chai-An. Mao, et.al., Neuronal transcriptional repressor REST suppresses an Atoh7-independent program for initiating retinal ganglion cell development., Developmental biology, 2011, 349
  http://rdf.ncbi.nlm.nih.gov/pubmed/20969844