decreased anxiety-related response_Pla2g4a<tm1Jvb>/Pla2g4a<tm1Jvb>,Tg(PDGFB-APPSwInd)20Lms/0

http://metadb.riken.jp/0001364I129S4SvJaeC57BL6DBA2Pla2g4atm1JvbPla2g4atm1JvbTgPDGFBAPPSwInd20Lms0Pla2g4atm1JvbTgPDGFBAPPSwInd20Lms

decreased anxiety-related response_Pla2g4a<tm1Jvb>/Pla2g4a<tm1Jvb>,Tg(PDGFB-APPSwInd)20Lms/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• phospholipase A2, group IVA (cytosolic, calcium-dependent)
  http://metadb.riken.jp/db/mgi_rdf/MGI:1195256
• transgene insertion 20, Lennart Mucke
  http://metadb.riken.jp/db/mgi_rdf/MGI:3057146

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pla2g4a<tm1Jvb>/Pla2g4a<tm1Jvb>,Tg(PDGFB-APPSwInd)20Lms/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pla2g4a<tm1Jvb>|Tg(PDGFB-APPSwInd)20Lms

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased anxiety-related response
  http://purl.obolibrary.org/obo/MP_0001364

文献

http://purl.org/net/cito/citesAsAuthority

• Rene O. Sanchez-Mejia, et.al., Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease., Nature neuroscience, 2008, 11
  http://rdf.ncbi.nlm.nih.gov/pubmed/18931664