hyperactivity_Crhr1<tm2Wrst>/Crhr1<tm2Wrst>,Neurod6<tm1(cre)Kan>/Neurod6<+>

http://metadb.riken.jp/0001399I129S1Sv129S2SvPas129X1SvJC57BL6JCrhr1tm2WrstCrhr1tm2WrstNeurod6tm1creKanNeurod6Neurod6Neurod6tm1creKanCrhr1tm2Wrst

hyperactivity_Crhr1<tm2Wrst>/Crhr1<tm2Wrst>,Neurod6<tm1(cre)Kan>/Neurod6<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• corticotropin releasing hormone receptor 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:88498
• neurogenic differentiation 6
  http://metadb.riken.jp/db/mgi_rdf/MGI:106593

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Crhr1<tm2Wrst>/Crhr1<tm2Wrst>,Neurod6<tm1(cre)Kan>/Neurod6<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Neurod6<+>|Neurod6<tm1(cre)Kan>|Crhr1<tm2Wrst>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• hyperactivity
  http://purl.obolibrary.org/obo/MP_0001399

文献

http://purl.org/net/cito/citesAsAuthority

• Damian. Refojo, et.al., Glutamatergic and dopaminergic neurons mediate anxiogenic and anxiolytic effects of CRHR1., Science (New York, N.Y.), 2011, 333
  http://rdf.ncbi.nlm.nih.gov/pubmed/21885734