hyperactivity_Tg(MT1A-Dyrk1a)#Xest/0

http://metadb.riken.jp/0001399IC57BL6SJLTgMT1ADyrk1aXest0TgMT1ADyrk1aXest

hyperactivity_Tg(MT1A-Dyrk1a)#Xest/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion #, Xavier Estivill
  http://metadb.riken.jp/db/mgi_rdf/MGI:3814564

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(MT1A-Dyrk1a)#Xest/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(MT1A-Dyrk1a)#Xest

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• hyperactivity
  http://purl.obolibrary.org/obo/MP_0001399

文献

http://purl.org/net/cito/citesAsAuthority

• X. Altafaj, et.al., Neurodevelopmental delay, motor abnormalities and cognitive deficits in transgenic mice overexpressing Dyrk1A (minibrain), a murine model of Down's syndrome., Human molecular genetics, 2001, 10
  http://rdf.ncbi.nlm.nih.gov/pubmed/11555628
• Jon. Ortiz-Abalia, et.al., Targeting Dyrk1A with AAVshRNA attenuates motor alterations in TgDyrk1A, a mouse model of Down syndrome., American journal of human genetics, 2008, 83
  http://rdf.ncbi.nlm.nih.gov/pubmed/18940310