impaired coordination_Tg(YAC128)53Hay/0

http://metadb.riken.jp/0001405FVBNTgYAC12853HayTgYAC12853Hay0TgYAC12853Hay

impaired coordination_Tg(YAC128)53Hay/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 53, Michael Hayden
  http://metadb.riken.jp/db/mgi_rdf/MGI:3613512

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(YAC128)53Hay/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(YAC128)53Hay

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• FVB/N-Tg(YAC128)53Hay

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• impaired coordination
  http://purl.obolibrary.org/obo/MP_0001405

文献

http://purl.org/net/cito/citesAsAuthority

• Rona K. Graham, et.al., Levels of mutant huntingtin influence the phenotypic severity of Huntington disease in YAC128 mouse models., Neurobiology of disease, 2006, 21
  http://rdf.ncbi.nlm.nih.gov/pubmed/16230019
• Rona K. Graham, et.al., Cleavage at the caspase-6 site is required for neuronal dysfunction and degeneration due to mutant huntingtin., Cell, 2006, 125
  http://rdf.ncbi.nlm.nih.gov/pubmed/16777606
• Elizabeth J. Slow, et.al., Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease., Human molecular genetics, 2003, 12
  http://rdf.ncbi.nlm.nih.gov/pubmed/12812983