impaired coordination_Tg(HTT*97Q)IXwy/0

http://metadb.riken.jp/0001405FVBTgHTT97QIXwyTgHTT97QIXwy0TgHTT97QIXwy

impaired coordination_Tg(HTT*97Q)IXwy/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion I, X William Yang
  http://metadb.riken.jp/db/mgi_rdf/MGI:3800752

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(HTT*97Q)IXwy/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(HTT*97Q)IXwy

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• FVB-Tg(HTT*97Q)IXwy

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• impaired coordination
  http://purl.obolibrary.org/obo/MP_0001405

文献

http://purl.org/net/cito/citesAsAuthority

• Liliana. Menalled, et.al., Systematic behavioral evaluation of Huntington's disease transgenic and knock-in mouse models., Neurobiology of disease, 2009, 35
  http://rdf.ncbi.nlm.nih.gov/pubmed/19464370
• Michelle. Gray, et.al., Full-length human mutant huntingtin with a stable polyglutamine repeat can elicit progressive and selective neuropathogenesis in BACHD mice., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, 28
  http://rdf.ncbi.nlm.nih.gov/pubmed/18550760
• Nan. Wang, et.al., Neuronal targets for reducing mutant huntingtin expression to ameliorate disease in a mouse model of Huntington's disease., Nature medicine, 2014, 20
  http://rdf.ncbi.nlm.nih.gov/pubmed/24784230
• Xiaofeng. Gu, et.al., Serines 13 and 16 are critical determinants of full-length human mutant huntingtin induced disease pathogenesis in HD mice., Neuron, 2009, 64
  http://rdf.ncbi.nlm.nih.gov/pubmed/20064390