impaired coordination_Tg(Thy1-MAPT)1Vln/Tg(Thy1-MAPT)1Vln

http://metadb.riken.jp/0001405IFVBTgThy1MAPT1VlnTgThy1MAPT1VlnTgThy1MAPT1Vln

impaired coordination_Tg(Thy1-MAPT)1Vln/Tg(Thy1-MAPT)1Vln

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Fred Van Leuven
  http://metadb.riken.jp/db/mgi_rdf/MGI:3720110

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Thy1-MAPT)1Vln/Tg(Thy1-MAPT)1Vln

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Thy1-MAPT)1Vln

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: FVB

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• impaired coordination
  http://purl.obolibrary.org/obo/MP_0001405

文献

http://purl.org/net/cito/citesAsAuthority

• K. Spittaels, et.al., Prominent axonopathy in the brain and spinal cord of transgenic mice overexpressing four-repeat human tau protein., The American journal of pathology, 1999, 155
  http://rdf.ncbi.nlm.nih.gov/pubmed/10595944
• K. Spittaels, et.al., Glycogen synthase kinase-3beta phosphorylates protein tau and rescues the axonopathy in the central nervous system of human four-repeat tau transgenic mice., The Journal of biological chemistry, 2000, 275
  http://rdf.ncbi.nlm.nih.gov/pubmed/11007782