polyphagia_Mc4r<tm2Lowl>/Mc4r<tm2Lowl>,Slc17a6<tm2(cre)Lowl>/Slc17a6<+>

http://metadb.riken.jp/0001433I129S4SvJaeSor129S6SvEvTacC57BL6FVBNMc4rtm2LowlMc4rtm2LowlSlc17a6tm2creLowlSlc17a6Mc4rtm2LowlSlc17a6tm2creLowlSlc17a6

polyphagia_Mc4r<tm2Lowl>/Mc4r<tm2Lowl>,Slc17a6<tm2(cre)Lowl>/Slc17a6<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• melanocortin 4 receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:99457
• solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
  http://metadb.riken.jp/db/mgi_rdf/MGI:2156052

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Mc4r<tm2Lowl>/Mc4r<tm2Lowl>,Slc17a6<tm2(cre)Lowl>/Slc17a6<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Mc4r<tm2Lowl>|Slc17a6<tm2(cre)Lowl>|Slc17a6<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• polyphagia
  http://purl.obolibrary.org/obo/MP_0001433

文献

http://purl.org/net/cito/citesAsAuthority

• Bhavik P. Shah, et.al., MC4R-expressing glutamatergic neurons in the paraventricular hypothalamus regulate feeding and are synaptically connected to the parabrachial nucleus., Proceedings of the National Academy of Sciences of the United States of America, 2014, 111
  http://rdf.ncbi.nlm.nih.gov/pubmed/25157144