abnormal spatial learning_Bace1<tm1Pcw>/Bace1<+>,Tg(APP695)3Dbo/0,Tg(PSEN1dE9)S9Dbo/0

http://metadb.riken.jp/0001463I129S1Sv129X1SvJC3HHeJC57BL6JBace1tm1PcwBace1TgAPP6953Dbo0TgPSEN1dE9S9Dbo0TgAPP6953DboTgPSEN1dE9S9DboBace1tm1PcwBace1

abnormal spatial learning_Bace1<tm1Pcw>/Bace1<+>,Tg(APP695)3Dbo/0,Tg(PSEN1dE9)S9Dbo/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 3, David R Borchelt
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448606
• beta-site APP cleaving enzyme 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1346542
• transgene insertion S9, David R Borchelt
  http://metadb.riken.jp/db/mgi_rdf/MGI:3618598

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Bace1<tm1Pcw>/Bace1<+>,Tg(APP695)3Dbo/0,Tg(PSEN1dE9)S9Dbo/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(APP695)3Dbo|Tg(PSEN1dE9)S9Dbo|Bace1<tm1Pcw>|Bace1<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C3H/HeJ * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal spatial learning
  http://purl.obolibrary.org/obo/MP_0001463

文献

http://purl.org/net/cito/citesAsAuthority

• Fiona M. Laird, et.al., BACE1, a major determinant of selective vulnerability of the brain to amyloid-beta amyloidogenesis, is essential for cognitive, emotional, and synaptic functions., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, 25
  http://rdf.ncbi.nlm.nih.gov/pubmed/16354928