abnormal contextual conditioning behavior_Grin1<tm2Stl>/Grin1<tm2Stl>,Tg(Actb-tTA)1Jzt/0,Tg(Camk2a-cre)T29-1Stl/0,Tg(tetO-Grin1/GFP)1Jzt/0

http://metadb.riken.jp/0001469IC57BL6CBAGrin1tm2StlGrin1tm2StlTgActbtTA1Jzt0TgCamk2acreT291Stl0TgtetOGrin1GFP1Jzt0TgtetOGrin1GFP1JztGrin1tm2StlTgActbtTA1JztTgCamk2acreT291Stl

abnormal contextual conditioning behavior_Grin1<tm2Stl>/Grin1<tm2Stl>,Tg(Actb-tTA)1Jzt/0,Tg(Camk2a-cre)T29-1Stl/0,Tg(tetO-Grin1/GFP)1Jzt/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion T29-1, Susumu Tonegawa
  http://metadb.riken.jp/db/mgi_rdf/MGI:2177646
• transgene insertion 1, Joe Z Tsien
  http://metadb.riken.jp/db/mgi_rdf/MGI:3038602
• transgene insertion 1, Joe Z Tsien
  http://metadb.riken.jp/db/mgi_rdf/MGI:3038601
• glutamate receptor, ionotropic, NMDA1 (zeta 1)
  http://metadb.riken.jp/db/mgi_rdf/MGI:95819

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Grin1<tm2Stl>/Grin1<tm2Stl>,Tg(Actb-tTA)1Jzt/0,Tg(Camk2a-cre)T29-1Stl/0,Tg(tetO-Grin1/GFP)1Jzt/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(tetO-Grin1/GFP)1Jzt|Grin1<tm2Stl>|Tg(Actb-tTA)1Jzt|Tg(Camk2a-cre)T29-1Stl

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal contextual conditioning behavior
  http://purl.obolibrary.org/obo/MP_0001469

文献

http://purl.org/net/cito/citesAsAuthority

• E. Shimizu, et.al., NMDA receptor-dependent synaptic reinforcement as a crucial process for memory consolidation., Science (New York, N.Y.), 2000, 290
  http://rdf.ncbi.nlm.nih.gov/pubmed/11073458
• Zhenzhong. Cui, et.al., Inducible and reversible NR1 knockout reveals crucial role of the NMDA receptor in preserving remote memories in the brain., Neuron, 2004, 41
  http://rdf.ncbi.nlm.nih.gov/pubmed/15003177