impaired balance_Cacna1a<tm2.1Maag>/Cacna1a<tm2.1Maag>,Tg(Pcp2-cre)2Mpin/0

http://metadb.riken.jp/0001525I129P2OlaHsd129S1Sv129X1SvJCacna1atm21MaagCacna1atm21MaagTgPcp2cre2Mpin0Cacna1atm21MaagTgPcp2cre2Mpin

impaired balance_Cacna1a<tm2.1Maag>/Cacna1a<tm2.1Maag>,Tg(Pcp2-cre)2Mpin/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
  http://metadb.riken.jp/db/mgi_rdf/MGI:109482
• transgene insertion 2, Max-Planck-Institute of Neurobiology
  http://metadb.riken.jp/db/mgi_rdf/MGI:2137514

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cacna1a<tm2.1Maag>/Cacna1a<tm2.1Maag>,Tg(Pcp2-cre)2Mpin/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cacna1a<tm2.1Maag>|Tg(Pcp2-cre)2Mpin

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• impaired balance
  http://purl.obolibrary.org/obo/MP_0001525

文献

http://purl.org/net/cito/citesAsAuthority

• Boyan. Todorov, et.al., Purkinje cell-specific ablation of Cav2.1 channels is sufficient to cause cerebellar ataxia in mice., Cerebellum (London, England), 2012, 11
  http://rdf.ncbi.nlm.nih.gov/pubmed/21870131