impaired balance_Prnp<tm1Cwe>/Prnp<tm1Cwe>,Tg(Prnp*D177N*M128V)A21Rchi/0

http://metadb.riken.jp/0001525I129S7SvEvBrdC57BL6CBAPrnptm1CwePrnptm1CweTgPrnpD177NM128VA21Rchi0Prnptm1CweTgPrnpD177NM128VA21Rchi

impaired balance_Prnp<tm1Cwe>/Prnp<tm1Cwe>,Tg(Prnp*D177N*M128V)A21Rchi/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion A21, Roberto Chiesa
  http://metadb.riken.jp/db/mgi_rdf/MGI:3836987
• prion protein
  http://metadb.riken.jp/db/mgi_rdf/MGI:97769

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Prnp<tm1Cwe>/Prnp<tm1Cwe>,Tg(Prnp*D177N*M128V)A21Rchi/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Prnp<tm1Cwe>|Tg(Prnp*D177N*M128V)A21Rchi

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• impaired balance
  http://purl.obolibrary.org/obo/MP_0001525

文献

http://purl.org/net/cito/citesAsAuthority

• Sara. Dossena, et.al., Mutant prion protein expression causes motor and memory deficits and abnormal sleep patterns in a transgenic mouse model., Neuron, 2008, 60
  http://rdf.ncbi.nlm.nih.gov/pubmed/19038218