increased circulating triglyceride level_Apoe<tm3(APOE*4)Mae>/Apoe<tm3(APOE*4)Mae>,Ldlr<tm1(LDLR)Mae>/Ldlr<+>

http://metadb.riken.jp/0001552I129P2OlaHsd129S7SvEvBrdC57BL6Apoetm3APOE4MaeApoetm3APOE4MaeLdlrtm1LDLRMaeLdlrLdlrApoetm3APOE4MaeLdlrtm1LDLRMae

increased circulating triglyceride level_Apoe<tm3(APOE*4)Mae>/Apoe<tm3(APOE*4)Mae>,Ldlr<tm1(LDLR)Mae>/Ldlr<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• apolipoprotein E
  http://metadb.riken.jp/db/mgi_rdf/MGI:88057
• low density lipoprotein receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:96765

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Apoe<tm3(APOE*4)Mae>/Apoe<tm3(APOE*4)Mae>,Ldlr<tm1(LDLR)Mae>/Ldlr<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ldlr<+>|Apoe<tm3(APOE*4)Mae>|Ldlr<tm1(LDLR)Mae>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased circulating triglyceride level
  http://purl.obolibrary.org/obo/MP_0001552

文献

http://purl.org/net/cito/citesAsAuthority

• Sudi I. Malloy, et.al., Harmful effects of increased LDLR expression in mice with human APOE*4 but not APOE*3., Arteriosclerosis, thrombosis, and vascular biology, 2004, 24
  http://rdf.ncbi.nlm.nih.gov/pubmed/12969990