hyperglycemia_Huwe1<tm1Wgu>/Y,Tg(Ins2-cre)23Herr/0,Trp53<tm1Thl>/Trp53<tm1Thl>

http://metadb.riken.jp/0001559IC57BL6JCBAJHuwe1tm1WguYTgIns2cre23Herr0Trp53tm1ThlTrp53tm1ThlTrp53tm1ThlTgIns2cre23HerrHuwe1tm1Wgu

hyperglycemia_Huwe1<tm1Wgu>/Y,Tg(Ins2-cre)23Herr/0,Trp53<tm1Thl>/Trp53<tm1Thl>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• HECT, UBA and WWE domain containing 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1926884
• transgene insertion 23, Pedro Luis Herrera
  http://metadb.riken.jp/db/mgi_rdf/MGI:4431238
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Huwe1<tm1Wgu>/Y,Tg(Ins2-cre)23Herr/0,Trp53<tm1Thl>/Trp53<tm1Thl>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<tm1Thl>|Tg(Ins2-cre)23Herr|Huwe1<tm1Wgu>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6J * CBA/J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• hyperglycemia
  http://purl.obolibrary.org/obo/MP_0001559

文献

http://purl.org/net/cito/citesAsAuthority

• Ning. Kon, et.al., Inactivation of arf-bp1 induces p53 activation and diabetic phenotypes in mice., The Journal of biological chemistry, 2012, 287
  http://rdf.ncbi.nlm.nih.gov/pubmed/22187431