abnormal myelopoiesis_Ctsg<tm2.1(PML/RARA)Ley>/Ctsg<+>,Elane<tm1Sds>/Elane<tm1Sds>

http://metadb.riken.jp/0001601I129SSvEv129X1SvJC57BL6Ctsgtm21PMLRARALeyCtsgElanetm1SdsElanetm1SdsCtsgElanetm1SdsCtsgtm21PMLRARALey

abnormal myelopoiesis_Ctsg<tm2.1(PML/RARA)Ley>/Ctsg<+>,Elane<tm1Sds>/Elane<tm1Sds>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cathepsin G
  http://metadb.riken.jp/db/mgi_rdf/MGI:88563
• elastase, neutrophil expressed
  http://metadb.riken.jp/db/mgi_rdf/MGI:2679229

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ctsg<tm2.1(PML/RARA)Ley>/Ctsg<+>,Elane<tm1Sds>/Elane<tm1Sds>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ctsg<+>|Elane<tm1Sds>|Ctsg<tm2.1(PML/RARA)Ley>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal myelopoiesis
  http://purl.obolibrary.org/obo/MP_0001601

文献

http://purl.org/net/cito/citesAsAuthority

• Andrew A. Lane, et.al., Neutrophil elastase cleaves PML-RARalpha and is important for the development of acute promyelocytic leukemia in mice., Cell, 2003, 115
  http://rdf.ncbi.nlm.nih.gov/pubmed/14636558