cardiac hypertrophy_Mapk1<tm1Melo>/Mapk1<+>,Tg(Myh6-Map2k1*)1Jmol/0

http://metadb.riken.jp/0001625I129S2SvPasFVBMapk1tm1MeloMapk1TgMyh6Map2k11Jmol0Mapk1Mapk1tm1MeloTgMyh6Map2k11Jmol

cardiac hypertrophy_Mapk1<tm1Melo>/Mapk1<+>,Tg(Myh6-Map2k1*)1Jmol/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Jeffery D Molkentin
  http://metadb.riken.jp/db/mgi_rdf/MGI:3766500
• mitogen-activated protein kinase 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1346858

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Mapk1<tm1Melo>/Mapk1<+>,Tg(Myh6-Map2k1*)1Jmol/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Mapk1<+>|Mapk1<tm1Melo>|Tg(Myh6-Map2k1*)1Jmol

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * FVB

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• cardiac hypertrophy
  http://purl.obolibrary.org/obo/MP_0001625

文献

http://purl.org/net/cito/citesAsAuthority

• Nicole H. Purcell, et.al., Genetic inhibition of cardiac ERK1/2 promotes stress-induced apoptosis and heart failure but has no effect on hypertrophy in vivo., Proceedings of the National Academy of Sciences of the United States of America, 2007, 104
  http://rdf.ncbi.nlm.nih.gov/pubmed/17709754