cardiac hypertrophy_Nfatc3<tm1Glm>/Nfatc3<tm1Glm>,Tg(Myh6-Ppp3ca)37Eno/?

http://metadb.riken.jp/0001625I129S2SvPasFVBNfatc3tm1GlmNfatc3tm1GlmTgMyh6Ppp3ca37EnoNfatc3tm1GlmTgMyh6Ppp3ca37Eno

cardiac hypertrophy_Nfatc3<tm1Glm>/Nfatc3<tm1Glm>,Tg(Myh6-Ppp3ca)37Eno/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 37, Eric N Olson
  http://metadb.riken.jp/db/mgi_rdf/MGI:3056183
• nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:103296

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Nfatc3<tm1Glm>/Nfatc3<tm1Glm>,Tg(Myh6-Ppp3ca)37Eno/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Nfatc3<tm1Glm>|Tg(Myh6-Ppp3ca)37Eno

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * FVB

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• cardiac hypertrophy
  http://purl.obolibrary.org/obo/MP_0001625

文献

http://purl.org/net/cito/citesAsAuthority

• Benjamin J. Wilkins, et.al., Targeted disruption of NFATc3, but not NFATc4, reveals an intrinsic defect in calcineurin-mediated cardiac hypertrophic growth., Molecular and cellular biology, 2002, 22
  http://rdf.ncbi.nlm.nih.gov/pubmed/12370307