cardiac hypertrophy_Atp1a2<tm4.1Ling>/Atp1a2<tm4.1Ling>,Tg(Tagln-cre)1Her/0

http://metadb.riken.jp/0001625IBlackSwissC57BL6SJLAtp1a2tm41LingAtp1a2tm41LingTgTaglncre1Her0TgTaglncre1HerAtp1a2tm41Ling

cardiac hypertrophy_Atp1a2<tm4.1Ling>/Atp1a2<tm4.1Ling>,Tg(Tagln-cre)1Her/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• ATPase, Na+/K+ transporting, alpha 2 polypeptide
  http://metadb.riken.jp/db/mgi_rdf/MGI:88106
• transgene insertion 1, Joachim Herz
  http://metadb.riken.jp/db/mgi_rdf/MGI:2450259

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Atp1a2<tm4.1Ling>/Atp1a2<tm4.1Ling>,Tg(Tagln-cre)1Her/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Tagln-cre)1Her|Atp1a2<tm4.1Ling>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: Black Swiss * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• cardiac hypertrophy
  http://purl.obolibrary.org/obo/MP_0001625

文献

http://purl.org/net/cito/citesAsAuthority

• Tara N. Rindler, et.al., Knockout of the Na,K-ATPase α₂-isoform in the cardiovascular system does not alter basal blood pressure but prevents ACTH-induced hypertension., American journal of physiology. Heart and circulatory physiology, 2011, 301
  http://rdf.ncbi.nlm.nih.gov/pubmed/21856916