cardiac hypertrophy_Arhgef1<tm1Rmt>/Arhgef1<tm1Rmt>,X/Tg(Myh11-cre/ERT2)1Soff

http://metadb.riken.jp/0001625IC57BL6FVBNArhgef1tm1RmtArhgef1tm1RmtXTgMyh11creERT21SoffArhgef1tm1RmtTgMyh11creERT21Soff

cardiac hypertrophy_Arhgef1<tm1Rmt>/Arhgef1<tm1Rmt>,X/Tg(Myh11-cre/ERT2)1Soff

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Stefan Offermanns
  http://metadb.riken.jp/db/mgi_rdf/MGI:3819268
• Rho guanine nucleotide exchange factor (GEF) 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1353510

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Arhgef1<tm1Rmt>/Arhgef1<tm1Rmt>,X/Tg(Myh11-cre/ERT2)1Soff

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Arhgef1<tm1Rmt>|Tg(Myh11-cre/ERT2)1Soff

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• cardiac hypertrophy
  http://purl.obolibrary.org/obo/MP_0001625

文献

http://purl.org/net/cito/citesAsAuthority

• Christophe. Guilluy, et.al., The Rho exchange factor Arhgef1 mediates the effects of angiotensin II on vascular tone and blood pressure., Nature medicine, 2010, 16
  http://rdf.ncbi.nlm.nih.gov/pubmed/20098430