hepatic necrosis_Igfbp1<tm1Taub>/Igfbp1<tm1Taub>

http://metadb.riken.jp/0001654I129X1SvJC57BL6Igfbp1tm1TaubIgfbp1tm1TaubIgfbp1tm1Taub

hepatic necrosis_Igfbp1<tm1Taub>/Igfbp1<tm1Taub>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• insulin-like growth factor binding protein 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:96436

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Igfbp1<tm1Taub>/Igfbp1<tm1Taub>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Igfbp1<tm1Taub>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• hepatic necrosis
  http://purl.obolibrary.org/obo/MP_0001654

文献

http://purl.org/net/cito/citesAsAuthority

• Julia I. Leu, et.al., Massive hepatic apoptosis associated with TGF-beta1 activation after Fas ligand treatment of IGF binding protein-1-deficient mice., The Journal of clinical investigation, 2003, 111
  http://rdf.ncbi.nlm.nih.gov/pubmed/12511596
• Julia I. Leu, et.al., Impaired hepatocyte DNA synthetic response posthepatectomy in insulin-like growth factor binding protein 1-deficient mice with defects in C/EBP beta and mitogen-activated protein kinase/extracellular signal-regulated kinase regulation., Molecular and cellular biology, 2003, 23
  http://rdf.ncbi.nlm.nih.gov/pubmed/12556485