hepatic necrosis_Braf<tm1Tumg>/Braf<+>,Tg(CAG-cre)2Osb/0

http://metadb.riken.jp/0001654IC57BLC57BL6JDBABraftm1TumgBrafTgCAGcre2Osb0TgCAGcre2OsbBrafBraftm1Tumg

hepatic necrosis_Braf<tm1Tumg>/Braf<+>,Tg(CAG-cre)2Osb/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• Braf transforming gene
  http://metadb.riken.jp/db/mgi_rdf/MGI:88190
• transgene insertion 2, Research Institute for Microbial Diseases, Osaka University
  http://metadb.riken.jp/db/mgi_rdf/MGI:3046676

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Braf<tm1Tumg>/Braf<+>,Tg(CAG-cre)2Osb/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(CAG-cre)2Osb|Braf<+>|Braf<tm1Tumg>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL * C57BL/6J * DBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• hepatic necrosis
  http://purl.obolibrary.org/obo/MP_0001654

文献

http://purl.org/net/cito/citesAsAuthority

• Shin-Ichi. Inoue, et.al., New BRAF knockin mice provide a pathogenetic mechanism of developmental defects and a therapeutic approach in cardio-facio-cutaneous syndrome., Human molecular genetics, 2014, 23
  http://rdf.ncbi.nlm.nih.gov/pubmed/25035421