abnormal embryo development_Mdm4<tm1Glo>/Mdm4<tm1Glo>,Trp53<tm1Tyj>/Trp53<+>

http://metadb.riken.jp/0001672I129S2SvPasMdm4tm1GloMdm4tm1GloTrp53tm1TyjTrp53Mdm4tm1GloTrp53Trp53tm1Tyj

abnormal embryo development_Mdm4<tm1Glo>/Mdm4<tm1Glo>,Trp53<tm1Tyj>/Trp53<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformed mouse 3T3 cell double minute 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:107934
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Mdm4<tm1Glo>/Mdm4<tm1Glo>,Trp53<tm1Tyj>/Trp53<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Mdm4<tm1Glo>|Trp53<+>|Trp53<tm1Tyj>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal embryogenesis/ development
  http://purl.obolibrary.org/obo/MP_0001672

文献

http://purl.org/net/cito/citesAsAuthority

• Tomoo. Iwakuma, et.al., Mutation at p53 serine 389 does not rescue the embryonic lethality in mdm2 or mdm4 null mice., Oncogene, 2004, 23
  http://rdf.ncbi.nlm.nih.gov/pubmed/15361844