abnormal postnatal growth_Tg(CAG-cre/Esr1*)5Amc/?,Thra<tm1Ffla>/Thra<+>

http://metadb.riken.jp/0001731I129SvC57BL6CBATgCAGcreEsr15AmcThratm1FflaThraTgCAGcreEsr15AmcThraThratm1Ffla

abnormal postnatal growth_Tg(CAG-cre/Esr1*)5Amc/?,Thra<tm1Ffla>/Thra<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• thyroid hormone receptor alpha
  http://metadb.riken.jp/db/mgi_rdf/MGI:98742
• transgene insertion 5, Andrew P McMahon
  http://metadb.riken.jp/db/mgi_rdf/MGI:2182765

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(CAG-cre/Esr1*)5Amc/?,Thra<tm1Ffla>/Thra<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(CAG-cre/Esr1*)5Amc|Thra<+>|Thra<tm1Ffla>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal postnatal growth
  http://purl.obolibrary.org/obo/MP_0001731

文献

http://purl.org/net/cito/citesAsAuthority

• Laure. Quignodon, et.al., A point mutation in the activation function 2 domain of thyroid hormone receptor alpha1 expressed after CRE-mediated recombination partially recapitulates hypothyroidism., Molecular endocrinology (Baltimore, Md.), 2007, 21
  http://rdf.ncbi.nlm.nih.gov/pubmed/17622582