abnormal homeostasis_Gclc<tm1Tdal>/Gclc<tm1Tdal>,Tg(Alb-cre)21Mgn/0

http://metadb.riken.jp/0001764I129S6SvEvTacC57BL6DBAGclctm1TdalGclctm1TdalTgAlbcre21Mgn0TgAlbcre21MgnGclctm1Tdal

abnormal homeostasis_Gclc<tm1Tdal>/Gclc<tm1Tdal>,Tg(Alb-cre)21Mgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 21, Mark A Magnuson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176226
• glutamate-cysteine ligase, catalytic subunit
  http://metadb.riken.jp/db/mgi_rdf/MGI:104990

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gclc<tm1Tdal>/Gclc<tm1Tdal>,Tg(Alb-cre)21Mgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Alb-cre)21Mgn|Gclc<tm1Tdal>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6 * DBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal homeostasis
  http://purl.obolibrary.org/obo/MP_0001764

文献

http://purl.org/net/cito/citesAsAuthority

• Ying. Chen, et.al., Hepatocyte-specific Gclc deletion leads to rapid onset of steatosis with mitochondrial injury and liver failure., Hepatology (Baltimore, Md.), 2007, 45
  http://rdf.ncbi.nlm.nih.gov/pubmed/17464988