abnormal homeostasis_Sord<C57BL/Lia>/Sord<C57BL/Lia>,Tg(Cryaa-AKR1B1)222Smch/Tg(Cryaa-AKR1B1)222Smch

http://metadb.riken.jp/0001764IC57BLCBASordC57BLLiaSordC57BLLiaTgCryaaAKR1B1222SmchTgCryaaAKR1B1222SmchSordC57BLLiaTgCryaaAKR1B1222Smch

abnormal homeostasis_Sord<C57BL/Lia>/Sord<C57BL/Lia>,Tg(Cryaa-AKR1B1)222Smch/Tg(Cryaa-AKR1B1)222Smch

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 222, Stephen SM Chung
  http://metadb.riken.jp/db/mgi_rdf/MGI:3783826
• sorbitol dehydrogenase
  http://metadb.riken.jp/db/mgi_rdf/MGI:98266

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Sord<C57BL/Lia>/Sord<C57BL/Lia>,Tg(Cryaa-AKR1B1)222Smch/Tg(Cryaa-AKR1B1)222Smch

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Sord<C57BL/Lia>|Tg(Cryaa-AKR1B1)222Smch

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal homeostasis
  http://purl.obolibrary.org/obo/MP_0001764

文献

http://purl.org/net/cito/citesAsAuthority

• A Y. Lee, et.al., Demonstration that polyol accumulation is responsible for diabetic cataract by the use of transgenic mice expressing the aldose reductase gene in the lens., Proceedings of the National Academy of Sciences of the United States of America, 1995, 92
  http://rdf.ncbi.nlm.nih.gov/pubmed/7708723