abnormal iron level_Hfe2<tm1Nca>/Hfe2<+>,Tmprss6<tm1Dgen>/Tmprss6<tm1Dgen>

http://metadb.riken.jp/0001770I129P2OlaHsd129S4SvJae129S6SvEvTacC57BL6Hfe2tm1NcaHfe2Tmprss6tm1DgenTmprss6tm1DgenHfe2tm1NcaHfe2Tmprss6tm1Dgen

abnormal iron level_Hfe2<tm1Nca>/Hfe2<+>,Tmprss6<tm1Dgen>/Tmprss6<tm1Dgen>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transmembrane serine protease 6
  http://metadb.riken.jp/db/mgi_rdf/MGI:1919003
• hemochromatosis type 2 (juvenile)
  http://metadb.riken.jp/db/mgi_rdf/MGI:1916835

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Hfe2<tm1Nca>/Hfe2<+>,Tmprss6<tm1Dgen>/Tmprss6<tm1Dgen>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Hfe2<tm1Nca>|Hfe2<+>|Tmprss6<tm1Dgen>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S4/SvJae * 129S6/SvEvTac * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal iron level
  http://purl.obolibrary.org/obo/MP_0001770

文献

http://purl.org/net/cito/citesAsAuthority

• Karin E. Finberg, et.al., Down-regulation of Bmp/Smad signaling by Tmprss6 is required for maintenance of systemic iron homeostasis., Blood, 2010, 115
  http://rdf.ncbi.nlm.nih.gov/pubmed/20200349