decreased white adipose tissue amount_Mark2<tm1Hpw>/Mark2<tm1Hpw>

http://metadb.riken.jp/0001783I129X1SvJC57BL6Mark2tm1HpwMark2tm1HpwMark2tm1Hpw

decreased white adipose tissue amount_Mark2<tm1Hpw>/Mark2<tm1Hpw>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• MAP/microtubule affinity regulating kinase 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:99638

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Mark2<tm1Hpw>/Mark2<tm1Hpw>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Mark2<tm1Hpw>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased white adipose tissue amount
  http://purl.obolibrary.org/obo/MP_0001783

文献

http://purl.org/net/cito/citesAsAuthority

• Jochen K. Lennerz, et.al., Loss of Par-1a/MARK3/C-TAK1 kinase leads to reduced adiposity, resistance to hepatic steatosis, and defective gluconeogenesis., Molecular and cellular biology, 2010, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/20733003
• Jonathan B. Hurov, et.al., Loss of the Par-1b/MARK2 polarity kinase leads to increased metabolic rate, decreased adiposity, and insulin hypersensitivity in vivo., Proceedings of the National Academy of Sciences of the United States of America, 2007, 104
  http://rdf.ncbi.nlm.nih.gov/pubmed/17372192