impaired macrophage phagocytosis_Itgav<tm2Hyn>/Itgav<tm2.1Hyn>,Lyz2<tm1(cre)Ifo>/Lyz2<+>

http://metadb.riken.jp/0001798I129P2OlaHsd129S2SvPasC57BL6FVBItgavtm2HynItgavtm21HynLyz2tm1creIfoLyz2Lyz2Lyz2tm1creIfoItgavtm21HynItgavtm2Hyn

impaired macrophage phagocytosis_Itgav<tm2Hyn>/Itgav<tm2.1Hyn>,Lyz2<tm1(cre)Ifo>/Lyz2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• integrin alpha V
  http://metadb.riken.jp/db/mgi_rdf/MGI:96608
• lysozyme 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:96897

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Itgav<tm2Hyn>/Itgav<tm2.1Hyn>,Lyz2<tm1(cre)Ifo>/Lyz2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lyz2<+>|Lyz2<tm1(cre)Ifo>|Itgav<tm2.1Hyn>|Itgav<tm2Hyn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * FVB

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• impaired macrophage phagocytosis
  http://purl.obolibrary.org/obo/MP_0001798

文献

http://purl.org/net/cito/citesAsAuthority

• Adam. Lacy-Hulbert, et.al., Ulcerative colitis and autoimmunity induced by loss of myeloid alphav integrins., Proceedings of the National Academy of Sciences of the United States of America, 2007, 104
  http://rdf.ncbi.nlm.nih.gov/pubmed/17895374