impaired macrophage phagocytosis_Ldlr<tm1Her>/Ldlr<tm1Her>,Lrp1<tm2Her>/Lrp1<tm2Her>,Lyz2<tm1(cre)Ifo>/Lyz2<+>

http://metadb.riken.jp/0001798I129P2OlaHsd129S7SvEvBrdLdlrtm1HerLdlrtm1HerLrp1tm2HerLrp1tm2HerLyz2tm1creIfoLyz2Lyz2tm1creIfoLrp1tm2HerLyz2Ldlrtm1Her

impaired macrophage phagocytosis_Ldlr<tm1Her>/Ldlr<tm1Her>,Lrp1<tm2Her>/Lrp1<tm2Her>,Lyz2<tm1(cre)Ifo>/Lyz2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• low density lipoprotein receptor-related protein 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:96828
• low density lipoprotein receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:96765
• lysozyme 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:96897

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ldlr<tm1Her>/Ldlr<tm1Her>,Lrp1<tm2Her>/Lrp1<tm2Her>,Lyz2<tm1(cre)Ifo>/Lyz2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lyz2<tm1(cre)Ifo>|Lrp1<tm2Her>|Lyz2<+>|Ldlr<tm1Her>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S7/SvEvBrd

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• impaired macrophage phagocytosis
  http://purl.obolibrary.org/obo/MP_0001798

文献

http://purl.org/net/cito/citesAsAuthority

• Anna P. Lillis, et.al., Murine low-density lipoprotein receptor-related protein 1 (LRP) is required for phagocytosis of targets bearing LRP ligands but is not required for C1q-triggered enhancement of phagocytosis., Journal of immunology (Baltimore, Md. : 1950), 2008, 181
  http://rdf.ncbi.nlm.nih.gov/pubmed/18566402