impaired macrophage phagocytosis_Fgr<tm1Hev>/Fgr<tm1Hev>,Hck<tm1Hev>/Hck<tm1Hev>

http://metadb.riken.jp/0001798I129S7SvEvBrdC57BL6JFgrtm1HevFgrtm1HevHcktm1HevHcktm1HevHcktm1HevFgrtm1Hev

impaired macrophage phagocytosis_Fgr<tm1Hev>/Fgr<tm1Hev>,Hck<tm1Hev>/Hck<tm1Hev>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• FGR proto-oncogene, Src family tyrosine kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:95527
• hemopoietic cell kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:96052

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Fgr<tm1Hev>/Fgr<tm1Hev>,Hck<tm1Hev>/Hck<tm1Hev>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Hck<tm1Hev>|Fgr<tm1Hev>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• impaired macrophage phagocytosis
  http://purl.obolibrary.org/obo/MP_0001798

文献

http://purl.org/net/cito/citesAsAuthority

• C A. Lowell, et.al., Functional overlap in the src gene family: inactivation of hck and fgr impairs natural immunity., Genes & development, 1994, 8
  http://rdf.ncbi.nlm.nih.gov/pubmed/8125254